Nrf2-IN-3 (Compound R16), a Nrf2 inhibitor, binds to KEAP1 mutants (G333C mKEAP1) thereby restoring the impaired KEAP1/NRF2 interactions. This restoration sensitizes KEAP1-mutant cancer cells to chemotherapeutic agents, such as Cisplatin and Gefitinib, b
Molecular Weight:
442.53
CAS Number:
[6325-13-9]
Formula:
C22H26N4O4S
Target:
Others
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