MET/PDGFRA-IN-1 (compound 8c) is an inhibitor of MET and PDGFRA proteins, with an IC50 of 36 µM against MET. It inhibits MET phosphorylation, induces apoptosis, and reduces proliferation in various MET-positive cell lines, showing IC50 values of 15.3 µM
Molecular Weight:
449.51
Formula:
C26H23N7O
Target:
c-Met/HGFR
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