JBI-589 is an isoform-selective, non-covalent inhibitor of PAD4 that diminishes CXCR2 expression and impedes neutrophil chemotaxis. Additionally, it attenuates primary tumor growth and metastases, augmenting the efficacy of checkpoint inhibitors [1].
Molecular Weight:
481.56
CAS Number:
[2308504-22-3]
Formula:
C29H28FN5O
Target:
Others
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