WWL0245 is a potent and selective BRD4-targeting PROTAC that exhibits sub-nanomolar degradation efficiency (DC50 < 1 nM) for BRD4 over BRD2/3 and PLK1 (DC50 > 1 µM). It demonstrates pronounced selective cytotoxicity in BETi-sensitive cancer cell lines, p
Molecular Weight:
873.96
CAS Number:
[2869057-11-2]
Formula:
C45H51N11O8
Target:
Epigenetic Reader Domain
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