FEN1-IN-6 (compound 9) is a potent Flap endonuclease-1 (FEN1, IC50 = 10 nM) inhibitor, crucial for DNA damage repair in mammalian cells, and additionally targets the related endonuclease xeroderma pigmentosum G (XPG) with an IC50 of 23 nM [1].
Molecular Weight:
324.33
CAS Number:
[824983-84-8]
Formula:
C12H8N2O5S2
Target:
FLAP
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