DQn-1, a potent antifolate, demonstrates efficacy against Mycobacterium tuberculosis (Mtb) with an MIC 90 of 0.03 µM. It inhibits the DHFR enzyme, exhibiting IC 50 values of 8.7 nM for Mtb DHFR and 7.6 nM for the human counterpart [1].
Molecular Weight:
343.77
CAS Number:
[57343-54-1]
Formula:
C16H14ClN5O2
Target:
Others
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