EGFR-IN-81 (Compound 10i), an EGFR inhibitor, demonstrates potent activity by inhibiting EGFR WT and the L858R/T790M mutation at IC50 values of 4.38 nM and 5.69 nM, respectively. It also exhibits cytotoxic effects against MCF-7 and HCT116 cell lines with
Molecular Weight:
551.52
Formula:
C28H24F3N5O4
Target:
EGFR
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