PARP-1-IN-13 (Compound 19c) is a potent PARP-1 inhibitor with an IC50 of 26 nM, hindering DNA single-strand break repair and exacerbating DNA double-strand breaks. It induces apoptosis in cancer cells via the mitochondrial pathway [1].
Molecular Weight:
391.45
Formula:
C20H17N5O2S
Target:
PARP
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