Antiproliferative Agent-34 (Compound A14), a multitarget kinase inhibitor, demonstrates IC50 values of 177 nM for EGFR L858R/T790M and 1567 nM for EGFR WT. Additionally, it inhibits JAK2, ROS1, FLT3, FLT4, and PDGFRalpha with respective IC50s of 30.93 nM, 10
Molecular Weight:
529.55
CAS Number:
[2910858-34-1]
Formula:
C27H27N7O5
Target:
EGFR
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