YF704 (compound 4w), a selective allosteric inhibitor of SHP2, exhibits antiproliferative effects and induces apoptosis in cancer cells with an IC50 of 0.25 µM. Furthermore, it downregulates Erk1/2 and Akt phosphorylation levels in cancer cells [1].
Molecular Weight:
431.4
Formula:
C17H20Cl2N4OS2
Target:
Others
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