SA-VA, an intracellular self-assembled PROTAC featuring azide and alkyne groups, selectively degrades VEGFR-2 and EphB4 proteins within U87 cells. This compound undergoes in situ conversion to active PROTAC via a copper-catalyzed click reaction utilizing
Molecular Weight:
1044.54
Formula:
C50H53ClF3N11O7S
Target:
PROTACs
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