PARP1-IN-14 (compound 19k) is a potent PARP1 inhibitor demonstrating an inhibition concentration (IC50) of 0.6 0.1 nM. It shows an antiproliferative effect on MDA-MB-436 (BRCA1 -/-) and Capan-1 (BRCA2 -/-) cells, with IC50 values under 0.3 nM [1].
Molecular Weight:
525.53
CAS Number:
[2098639-70-2]
Formula:
C28H24FN7O3
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