SPC-180002, a dual SIRT1/3 inhibitor, exhibits IC50 values of 1.13 and 5.41 µM for SIRT1 and SIRT3, respectively. It disrupts redox homeostasis through ROS generation, consequently enhancing p21 protein stability and inducing mitochondrial dysfunction. F
Molecular Weight:
317.38
CAS Number:
[2170274-53-8]
Formula:
C18H23NO4
Target:
Sirtuin
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