ZNL-05-044, a CDK11 inhibitor, exhibits IC50 values of 0.23 µM for CDK11A and 0.27 µM for CDK11B, as determined by NanoBRET assay. It induces G2/M cell cycle arrest and disrupts RNA splicing [1].
Molecular Weight:
477.41
Formula:
C21H22Cl2N6OS
Target:
CDK
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