PI3Kalpha-IN-13 (Compound 18a), a PI3Kalpha inhibitor with an IC50 of 2.5 nM, effectively induces apoptosis and hampers the proliferation of various cancer cell lines, exhibiting IC50 values of 0.75 µM (MCF-7), 3.79 µM (HCT-116), 13.71 µM (MDA-MB-231), and 9.85
Molecular Weight:
389.41
CAS Number:
[2955529-67-4]
Formula:
C21H19N5O3
Target:
PI3K
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