Compound A5b, also known as JMJD3/HDAC-IN-1, is a dual inhibitor that targets both JMJD3 (Jumonji domain-containing protein demethylase 3) and HADC1 (histone deacetylase, IC50 = 16 nM). It induces hypermethylation of histone H3K27 and hyperacetylation of
Molecular Weight:
398.5
CAS Number:
[2883046-06-6]
Formula:
C21H30N6O2
Target:
HDAC
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