VHL-IN-1 (compound 30), a ubiquitin E3 ligase von Hippel-Lindau (VHL) inhibitor with a dissociation constant (Kd) of 37 nM, potently stabilizes HIF-1alpha and enhances its transcriptional activity. It shows promise for applications as a HIF-1alpha stabilizer and
Molecular Weight:
544.68
Formula:
C28H37FN4O4S
Target:
HIF/HIF Prolyl-Hydroxylase
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