BQZ-485, a potent GDI2 inhibitor, interacts with Tyr245 to disrupt the native GDI2-Rab1A interaction. This disruption impedes vesicular transport from the endoplasmic reticulum (ER) to the Golgi apparatus, triggering subsequent paraptosis events [1].
Molecular Weight:
485.66
CAS Number:
[1906915-49-8]
Formula:
C32H39NO3
Target:
Apoptosis
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