PHD-IN-1 (compound 80) serves as a potent PHD2 inhibitor, exhibiting an IC50 value of 5 nM. It demonstrates EC50 values of 2.5 µM in EPO Elisa assays within both Caco2-HIF1a-HiBiT-clone-1 and Hep3B cell lines [1].
Molecular Weight:
441.49
CAS Number:
[2924182-31-8]
Formula:
C24H23N7O2
Target:
HIF/HIF Prolyl-Hydroxylase
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