ROCK-IN-9 (Compound T345), a ROCK inhibitor, exhibits cytotoxicity in HepG2 cells with an IC50 of 40.8 µM. It demonstrates favorable pharmacokinetic properties in mice, achieving high in vivo exposure and oral bioavailability at low doses [1].
Molecular Weight:
381.4
CAS Number:
[2643334-76-1]
Formula:
C20H20FN5O2
Target:
ROCK
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