D-4-77 is a potent inhibitor of SARS-CoV-2 Mpro, with an IC50 of 0.95 µM, and exhibits antiviral activity with an EC50 of 0.49 µM. Additionally, it suppresses SARS-CoV-2 Mpro-induced antagonism of the host NF-kappaB innate immune response [1].
Molecular Weight:
512.44
Formula:
C23H34BrN3O5
Target:
SARS-CoV
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