PAK4-IN-3 (compound 27e) is a PAK4 inhibitor with an IC50 of 10 nM, demonstrating antiproliferative effects on A549 cells with an IC50 of 0.61µM. It induces concentration-dependent apoptosis in A549 cells and halts the cell cycle at the G0/G1 phase [1].
Target:
PAK
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