High affinity ligand for the NOP site (Ki = 1.5 nM). Antagonizes nociceptin-stimulated GTP binding in rat brain and the chronotropic effect of nociceptin on rat cardiomyocytes. However, displays potent agonist properties in vivo, inhibiting locomotor act
Molecular Weight:
939.12
CAS Number:
[200959-48-4]
Formula:
C44H70N14O9
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