Tripeptide substance P (SP) antagonist (IC50 = 90 µM). Also inhibits binding of SP to Mas-related GPCR (MRGPR) X2. Inhibits SP-induced IgE-independent degranulation of mast cells in vitro. Inhibits compound 48/80-induced MRGPRX2 activation and scratching
Molecular Weight:
697.78
CAS Number:
[126088-82-2]
Formula:
C38H43N5O8
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