Potent Nav1.7 blocker (IC50 = 2.5 nM). Also inhibits Nav1.1, Nav1.2, Nav1.3 and Nav1.6 in the nanomolar range. Exhibits no effects on Cav channels or nAChR at 5 µM. Demonstrates analgesic activity in vivo, antagonizes effects of scorpion-venom toxin OD1
Molecular Weight:
3802.41
Formula:
C162H246N52O43S6
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