NFAT inhibitor. Inhibits LPS or LPS plus IFN-gamma-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). Also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. Improves symptoms in a mous
Molecular Weight:
3573.15
CAS Number:
[592517-80-1]
Formula:
C147H259N67O36S
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