Potent apelin receptor antagonist (Ki = 82 nM, IC50 = 93 nM). Antagonizes the inhibitory affect of [Pyr1]-Apelin-13 on forskolin-induced cAMP accumulation in CHO-K1-APJ cells. Recuces tumor expansion and lengthens survival time in a mouse xenograft model
Molecular Weight:
1737.15
CAS Number:
[1313027-43-8]
Formula:
C70H121N29O15S4
* VAT and and shipping costs not included. Errors and price changes excepted
