Potent and highly selective CRF2 receptor antagonist (Ki values are 0.66, 0.62 and 425 nM for human CRF2alpha, CRF2beta and CRF1 receptors respectively). Inhibits sauvagine-stimulated cAMP accumulation in hCRF2alpha- and hCRF2beta-expressing cells. In rats in vivo, bl
Molecular Weight:
3632.26
CAS Number:
[434938-41-7]
Formula:
C162H276N48O46
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