Selective HIF-1 dimerization inhibitor. Blocks protein-protein interaction of recombinant HIF-1alpha, but not HIF-2alpha, with HIF-1beta (IC50 = 1.3 µM). Inhibits hypoxia-induced HIF-1 activity, and decreases VEGF and CAIX expression in osteosarcoma and breast canc
Molecular Weight:
2559.1
CAS Number:
[1446322-66-2]
Formula:
C111H188N42O24S2
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