Antagonist of TrkB receptors, inhibits BDNF-induced TrkB activity (IC50 = 0.30 nM). Allosterically alters TrkB receptor conformation but does not alter BDNF binding. Prevents BDNF-induced cold allodynia in mice. Also shown to exhibit putative anxiolytic
Molecular Weight:
1200.36
CAS Number:
[1203586-72-4]
Formula:
C48H73N13O17S3
* VAT and and shipping costs not included. Errors and price changes excepted
