Potent irreversible alphaVbeta3 integrin antagonist (Ki = 0.27 nM). Disrupts attachment of osteoclasts to bone and inhibits bone reabsorption (IC50 = 0.1 nM). Prevents ADP-induced platelet aggregation via inhibition of glycoprotein IIb/IIIa (GpIIb/IIIa, alphaIIbbeta3)
Molecular Weight:
5417.1
CAS Number:
[154303-05-6]
Formula:
C217H341N71O74S9
Target:
Echistatin, alpha1 isoform
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