ADAM-17 (TACE) and MMP inhibitor (Ki = 120 nM at ADAM-17). Sensitizes cancer stem cells to the lethal effects of 5-FU in vitro. Blocks shedding of TNF-alpha from cell membranes.
Molecular Weight:
415.54
CAS Number:
[689284-12-6]
Formula:
C19H37N5O5
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