PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also an agonist of Mas-related gene 2 (MrgX2
Molecular Weight:
956.16
CAS Number:
[852629-88-0]
Formula:
C49H69N11O9
Target:
Complement System
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