Ilorasertib (ABT-348) (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (IC50s: 120 nM/7 nM/1 nM). It also suppresses RET tyrosine kinase, PDGFRbeta, and Flt1 (IC50s: 7 nM, 3 nM, and 32 nM).
Molecular Weight:
488.54
CAS Number:
[1227939-82-3]
Formula:
C25H21FN6O2S
Target:
ABT-348
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