Navtemadlin (AMG232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction (IC50: 0.6 nM). It binds to MDM2 with a Kd of 0.045 nM.
Molecular Weight:
568.55
CAS Number:
[1352066-68-2]
Formula:
C28H35Cl2NO5S
Target:
E1/E2/E3 Enzyme|||Mdm2
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