Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells (IC50 = 1 nM) and PBMCs (IC50 = 9 nM)
Molecular Weight:
349.47
CAS Number:
[558447-26-0]
Formula:
C21H27N5
Target:
CXCR
* VAT and and shipping costs not included. Errors and price changes excepted