Tirabrutinib (GS-4059) (ONO-4059) is an orally active Brutons Tyrosine Kinase (Btk) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib irreversibly and covalently binds to Btk and inhibits aberrant B cell receptor
Molecular Weight:
454.48
CAS Number:
[1351636-18-4]
Formula:
C25H22N6O3
Target:
BTK
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