Potent and selective inhibitor of CDKs. More potent than olomoucine. Inhibits CDK1/cyclin B kinase (IC50 = 450nM), CDK2 (IC50 = 700nM) and CDK5/p35 (IC50 = 160nM). Inhibits M phase promoting factor (MPF) kinase activity. Arrests human fibroblasts in G1 p
Molecular Weight:
354.5
Purity:
98% (NMR)
Form:
Supplied as a white to off-white solid.
CAS Number:
[186692-46-6]
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