PITPNM1, Recombinant, Human, aa1-238, GST-Tag (Membrane-associated Phosphatidylinositol Transfer Protein 1)

Catalog Number: USB-374715
Article Name: PITPNM1, Recombinant, Human, aa1-238, GST-Tag (Membrane-associated Phosphatidylinositol Transfer Protein 1)
Biozol Catalog Number: USB-374715
Supplier Catalog Number: 374715
Alternative Catalog Number: USB-374715-20,USB-374715-100,USB-374715-1
Manufacturer: US Biological
Category: Molekularbiologie
Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes. Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions. Source: Recombinant protein corresponding to aa1-238 from human PITPNM1, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~54.5kD Amino Acid Sequence: MLIKEYHILLPMSLDEYQVAQLYMIQKKSREESSGEGSGVEILANRPYTDGPGGSGQYTHKVYHVGSHIPGWFRALLPKAALQVEEESWNAYPYTRTRYTCPFVEKFSIEIETYYLPDGGQQPNVFNLSGAERRQRILDTIDIVRDAVAPGEYKAEEDPRLYHSVKTGRGPLSDDWARTAAQTGPLMCAYKLCKVEFRYWGMQAKIEQFIHDVGLRRVMLRAHRQAWCWQDEWTELSM Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight: 54.5
UniProt: O00562
Purity: 90% (SDS-PAGE)
Form: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.