RCHY1, Recombinant, Human, aa1-261, GST-Tag (RING Finger and CHY Zinc Finger Domain-containing Protein 1)

Product Overview

• Article Name: RCHY1, Recombinant, Human, aa1-261, GST-Tag (RING Finger and CHY Zinc Finger Domain-containing Protein 1)
• Biozol Catalog Number: USB-375012
• Supplier Catalog Number: 375012
• Alternative Catalog Number: USB-375012-20,USB-375012-100,USB-375012-1
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity. Source: Recombinant protein corresponding to aa1-261 from human RCHY1, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~57.1kD Amino Acid Sequence: MAATAREDGASGQERGQRGCEHYDRGCLLKAPCCDKLYTCRLCHDNNEDHQLDRFKVKEVQCINCEKIQHAQQTCEECSTLFGEYYCDICHLFDKDKKQYHCENCGICRIGPKEDFFHCLKCNLCLAMNLQGRHKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLHRTCYEEMLKEGYRCPLCMHSALDMTRYWRQLDDEVAQTPMPSEYQNMTVDILCNDCNGRSTVQFHILGMKCKICESYNTAQAGGRRISLDQQ Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 57.1
• UniProt: Q96PM5
• Purity: 90% (SDS-PAGE)
• Form: Supplied as a lyophilized powder from 20mM Tris-HCl, 0.5M sodium chloride, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O to a concentration of 0.1-1mg/ml.