IL17RB, Recombinant, Mouse, aa18-286, hIgG-His-Tag (Interleukin-17 Receptor B, Evi27, IL-17ER, IL-17Rh1, Il17br, IL17RH1)

Product Overview

• Article Name: IL17RB, Recombinant, Mouse, aa18-286, hIgG-His-Tag (Interleukin-17 Receptor B, Evi27, IL-17ER, IL-17Rh1, Il17br, IL17RH1)
• Biozol Catalog Number: USB-377856
• Supplier Catalog Number: 377856
• Alternative Catalog Number: USB-377856-50
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

Il17rb, also known as Interleukin-17 receptor B, is a cytokine receptor. This receptor specifically binds to IL17B and IL17E (IL25), but does not bind to IL17(A) or IL17C. It has been shown to mediate the activation of NF- kB and the production of IL8 induced by IL17E. It was found to be significantly up-regulated during intestinal inflammation, which suggested the immune regulatory activity of this receptor. Source: Recombinant protein corresponding to aa18-286 from mouse IL17RB, fused to hIgG-His-Tag at C-terminal, was expressed in insect cell. Molecular Weight: ~57.1kD (511aa), 57-70kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) AA Sequence: ADPREPTIQC GSETGPSPEW MVQHTLTPGD LRDLQVELVK TSVAAEEFSI LMNISWILRA DASIRLLKAT KICVSGKNNM NSYSCVRCNY TEAFQSQTRP SGGKWTFSYV GFPVELSTLY LISAHNIPNA NMNEDSPSLS VNFTSPGCLN HVMKYKKQCT EAGSLWDPDI TACKKNEKMV EVNFTTNPLG NRYTILIQRD TTLGFSRVLE NKLMRTSVAI PVTEESEGAV VQLTPYLHTC GNDCIRREGT VVLCSETSAP IPPDDNRRML GGVEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Product Properties

• Molecular Weight: 57.1
• NCBI: 062529
• UniProt: Q9JIP3
• Purity: ~90% (SDS-PAGE)
• Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.