Synthetic peptide corresponding to 12aa near the C-terminal of human TMPRSS2, located within 50aa of TMPRSS2. Species sequence homology: monkey (100%), gorilla (100%), feline (92%)
TMPRSS2 is a plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth fac