PX-866 ([(3aR,6E,9S,9aR,10R,11aS)-6-[[bis(prop-2-enyl)amino]methylidene]-5-hydroxy-9-(methoxymethyl)-9a,11a-dimethyl-1,4,7-trioxo-2,3,3a,9,10,11-hexahydroindeno[4,5-h]isochromen-10-yl] acetate, DJM-166, DJM-2-166), CAS [[502632-66

Product Overview

• Article Name: PX-866 ([(3aR,6E,9S,9aR,10R,11aS)-6-[[bis(prop-2-enyl)amino]methylidene]-5-hydroxy-9-(methoxymethyl)-9a,11a-dimethyl-1,4,7-trioxo-2,3,3a,9,10,11-hexahydroindeno[4,5-h]isochromen-10-yl] acetate, DJM-166, DJM-2-166), CAS [[502632-66
• Biozol Catalog Number: USB-P9394-50
• Supplier Catalog Number: P9394-50
• Alternative Catalog Number: USB-P9394-50-5
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

PX-866, a derivative of wortmannin, potently inhibited purified phosphoinositide (PtdIns)-3-kinase (IC50=0.1nM) and PtdIns-3-kinase signaling (IC50=20nM) as assessed by phospho-Ser473-Akt levels in HT-29 colon cancer cells. PX-866 showed antitumor activi

Product Properties

• Molecular Weight: 525.59
• Purity: ~99%
• Form: Supplied as a yellow crystalline
• CAS Number: [502632-66-8]