Heterogeneous nuclear ribonucleoproteins (hnRNP) bind to nascent RNA polymerase II transcripts and are involved in transcript-specific packaging as well as alternative splicing of pre-mRNAs. hnRNPs also appear to influence mRNA metabolism and transport.
Purity:
90% (SDS-PAGE), Purified by immunoaffinity chromatography.
Form:
Supplied as a liquid in 20mM Tris-HCI, 0.32M sodium chloride, 10mM magnesium chloride, 0.2mM DTT, pH 7.4, 0.1mM PMSF, 0.1% bromo-nitro-dioxane/ methylisothiazoline, 20% glycerol.
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