An active metabolite of Sulindac. Inhibits cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism. Inhibition of Ras activation of Ref-1. Impairs nucleotide exchange on Ras by CDC25 and accelerates Ras hydrolysis of GTP by p120GA
Molecular Weight:
340.41
Purity:
~90%
Form:
Yellow to Orange Solid
CAS Number:
[32004-67-4]
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