DNA topoisomerase I is a key nuclear enzyme that interconverts supercoiled DNA to the required topological conformations for normal DNA replication and transcription. This enzyme is the target antigen for the so-called Scl-70 autoantibodies. Scl-70 antib
Molecular Weight:
91.58
Purity:
95% (SDS-PAGE)
Form:
Supplied as a liquid in 16mM HEPES, pH 7.5, 400mM sodium chloride, 20% glycerol
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