Synthetic phosphopeptide corresponding to residues surrounding Tyr493 of human Zap-7. Species sequence homology: mouse and rat.
ZAP70, a Syk family protein tyrosine kinase expressed in T and NK cells, plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement (1). Following TCR engagement, ZAP70 is rapidly phosphorylated on several tyrosi