GST-fusion protein containing the 2 tandem SH2 domains of human ZAP-70 corresponding to aa1-254. Species sequence homology: rat
ZAP70, a 70kD member of the Syk tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. Mutations in ZAP70 gene results in a form of Severe Combined Immunodeficiency Syndrome (