Synthetic peptide corresponding to KWLDRYRQIRPCTS from the C-terminal of human ZRANB1. Species Sequence Homology: bovine, canine, mouse, porcine and rat
Positive regulator of the Wnt signaling pathway that specifically cleaves Lys-63-linked ubiquitin chains. Acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cyto