Pre-clinical AAV production and optimization

Not as easy as it looks!

GenscriptPresented by Nature Research Custom Media

Produced by Genscript

Speaker: Dr. Stephen Hughes, Director of New Platform Development at Genscript

Content

  • Introduction to AAV in gene therapy.
  • Some recent advances in viral vector production.
  • Current challenges and solutions of pre-clinical AAV production.

Adeno-associated virus (AAV) is the most popular vector of choice for gene therapy because of its low immunogenicity and ability to infect numerous cells and tissue types. However, with hundreds of gene therapy trials ongoing, manufacturing large quantities of viral vectors is becoming an increasing challenge.

 

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